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Specifically, the study assessed the safety and efficacy of ENoral rinse for prevention of ulcerative oral mucositis resulting from cytotoxic conditioning regimens administered prior to autologous bone marrow or peripheral stem cell transplant therapy. These indicated that EN did not meet its primary endpoint of preventing oral mucositis. Primary clinical endpoints were the presence or absence of ulcerative mucositis as well as the duration days of intraoral ulcers.

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Specifically, the study assessed the safety and efficacy of ENoral rinse for prevention of ulcerative oral mucositis resulting from cytotoxic conditioning regimens administered prior to autologous bone marrow or peripheral stem cell transplant therapy.

These indicated that EN did not meet its primary endpoint of preventing oral mucositis. Primary clinical endpoints were the presence or absence of ulcerative mucositis as well as the duration days of intraoral ulcers.

Severity of erythematous mucositis, oral pain and difficulty in swallowing also were assessed. Statistical ificance was not achieved in the comparison of active treatment versus vehicle or standard of care. Carol A.

Ammon, Chairman and Chief Executive Officer of Endo Pharmaceuticals, said, "Naturally, we are disappointed that we were unable to confirm the efficacy of EN in patients suffering from oral mucositis, exchage will continue to analyze the data from the program to determine the future of this product. The company researches, develops, produces and markets a broad product offering of branded and generic pharmaceuticals, meeting the needs of healthcare professionals and consumers alike.

More information, including this and past press releases of Endo Pharmaceuticals Holdings Inc. Forward-Looking Statements This press release contains forward-looking statements, within the meaning of Section 27A of the Securities Act of and Section 21E of the Securities Exchange Act ofas amended, that are based on management's beliefs and assumptions, current expectations, estimates and projections. Statements that are not historical facts, including statements which are preceded by, followed by, or that include, the words "believes," "anticipates," "plans," "expects" or similar expressions and statements are forward-looking statements.

Endo's estimated or anticipated future Lookign, product performance or other non- historical facts are forward-looking and reflect Endo's current perspective on existing trends and information. Many of the factors that will determine the Company's future are beyond the ability of the Company to control or predict.

These statements are subject to risks exxchange uncertainties and, therefore, actual may differ materially from those expressed or implied by these forward-looking statements. The reader should not rely on any forward-looking statement.

The Company undertakes no obligation to update any forward-looking statements whether as exxchange result of new orak, future events or otherwise. Several important factors, in addition to the specific factors discussed in connection with these forward-looking statements individually, could affect the future of Endo and could cause those to differ materially from those expressed in the forward-looking statements contained in this press release. Readers should evaluate any statement in light of these important factors.